Identification of a disseminated rhino­orbital­cerebral mucormycosis in mixed phenotype acute leukemia with Philadelphia chromosome positive

Abstract Mucormycosis (zygomycosis) is a globally invasive fungal infection that rarely occurs in immunocompetent but frequently in immunocompromised patients and is associated with high morbidity and mortality. The biopsy is the preferred method of diagnosis but may not be an option in the early course of the disease, resulting in delayed diagnosis and increased mortality. Herein, we presented a case of disseminated rhino­orbital-cerebral mucormycosis (ROCM) in mixed phenotype acute leukemia (MPAL) with Philadelphia (ph) chromosome positive and shared the therapy to it.