Phenolic and Triterpene Glycosides from the Stems ofIlexlitseaefolia

Chemical investigation on the stems of Ilex litseaefolia afforded four new phenolic glycosides, litseaefolosides A-D (1-4), and two new triterpene glycosides, spathodic acid 28-O-beta-D-glucopyranoside (5) and (20S)-niga-ichigoside F1 (6), along with 28 known compounds. The structures of 1-6 were determined on the basis of chemical and spectroscopic evidence. Litseaefoloside C (3) showed inhibitory activities in vitro for (x-glucosidase and lipase with IC50 values of 34.0 and 0.31 mu g/mL, respectively.