Oxytocin produced by neurons in fat tissue releases stored lipids

The hormone oxytocin is secreted by the brain during labour and lactation. It has also been associated with lipid release from intracellular stores, but the physiological implications of this were unknown. This study shows that oxytocin is produced locally by neurons that innervate the adipose tissue and is required for maximizing energy release from fat. A locally secreted hormone is required for breaking down stored fat and maximizing energy production.