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Base-promoted synthesis of 3-arylquinolines using DMSO as C1 source

Muhammad Asif Iqbal, Ali Raza Shah,Ruimao Hua

TETRAHEDRON LETTERS（2024）

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Abstract
The synthesis of 3-arylquinolines through a cyclocondensation of 2-aminoarylmethanols and benzaldehydes in DMSO promoted by KO t Bu has been developed. In this procedure, DMSO is used not only as a solvent, but also a C1 source incorporated into the 2 -position of quinoline ring.
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Key words
Dimethyl sulfoxide,2-aminoarylmethanols,Benzaldehydes,Cyclocondensation,Potassium tert -butoxide
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