Exploring the Impact of Saccharin on Neovascular Age-Related Macular Degeneration: A Comprehensive Study in Patients and Mice

Steffen E. Kuenzel,Inga-Marie Pompoes,Leonie T. M. Flesch,Dominik P. Frentzel,Vitus A. Knecht, Silvia Winkler,Sergej Skosyrski,Anne Ruebsam,Felix Dreher,Norbert Kociok,Moritz Schuette,Alexandre Dubrac,Bodo Lange,Marie-Laure Yaspo,Hans Lehrach,Olaf Strauss,Antonia M. Joussen,Oliver Zeitz

Investigative Ophthalmology & Visual Science（2024）

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neovascular age-related macular degeneration (nAMD),saccharin,artificial sweetener (AS),modifiable risk factors,intravitreal anti-VEGF treatment,treatment need,systems biology,choroidal neovascularization (CNV),inflammation,VEGF,complement factors

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