Redundant Pathways for Removal of Defective RNA Polymerase II Complexes at a Promoter-Proximal Pause Checkpoint

Daniel Blears, Jiangman Lou,Nova Fong,Richard Mitter,Ryan M. Sheridan, Dandan He,A. Barbara Dirac-Svejstrup,David Bentley,Jesper Q. Svejstrup

MOLECULAR CELL（2024）

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关键词

promoter-proximal pausing,Integrator,INTS6,protein phosphatase 2A,ARMC5,CUL3,DSIF,NELF,senataxin,mRNA capping,RNGTT,TFIIS,RNA polymerase II,RPB1,CTD phosphorylation,TFIIH kinase,pTEFb kinase,DRB,nascent transcription,TT-seq,eNET-seq

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