Dual-targeting tigecycline nanoparticles for treating intracranial infections caused by multidrug-resistant Acinetobacter baumannii

Xing Lan,Shugang Qin,Huan Liu,Mengran Guo,Yupei Zhang, Xinyang Jin,Xing Duan, Min Sun,Zhenjun Liu, Wenyan Wang,Qian Zheng,Xuelian Liao, Jinpeng Chen,Yan Kang,Yongmei Xie,Xiangrong Song

Journal of Nanobiotechnology（2024）

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摘要

Multidrug-resistant (MDR) Acinetobacter baumannii (A. baumannii) is a formidable pathogen responsible for severe intracranial infections post-craniotomy, exhibiting a mortality rate as high as 71

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关键词

Nanoparticles,Blood–brain barrier,Multidrug-resistant Acinetobacter baumannii,Tigecycline,Intracranial infection

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