Immune system dysregulation preceding a case of laboratory-confirmed zoster/dermatitis on board the International Space Station

Satish K. Mehta, PhD,Rahul Suresh, MD, Keith Brandt, MD, Douglass M. Diak, PhD,Scott M. Smith, PhD, Sara R. Zwart, PhD, Grace Douglas, PhD,Mayra Nelman-Gonzalez, BA, Simon Clemett, PhD,Tyson Brunstetter, OD, PhD,Brian E. Crucian, PhD

Journal of Allergy and Clinical Immunology: Global（2024）

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摘要

A case report detailing, for the first time, a case of laboratory-confirmed zoster in an astronaut on board the International Space Station is presented. The findings of reduced T-cell function, cytokine imbalance, and increased stress hormones which preceded the event are detailed. Relevance for deep space countermeasures is discussed.

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关键词

Immune system dysregulation,zoster,spaceflight,countermeasures

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