The Effects of hydroalcholic extract polyherbal formulation on improving the symptoms of patients with COVID-19 in hospital

Objectives: The pandemic of Coronavirus disease and severity of the infection and high mortality have almost unprecedented challenges in the health systems of most countries around the world. The present study aimed to evaluate the effect of hydroalcholic extract polyherbal formulation as entitled Imfluna on symptoms of COVID-19 infected patients. The polyherbal remedy for Imfluna had a significant effect on pulmonary involvement and reduced pulmonary involvement, the severity of shortness of breath, alanine aminotransferase (ALT), sodium (Na) in the post-test phase. Also, the average CBC count and percentage of blood oxygen saturation increased in both experimental and control groups. In addition to, the mean CBC count and percentage of blood oxygen saturation of the control group increased significantly. Methods: In this randomized double-blind placebo-controlled clinical trial a total of 60 voluntary confirmed COVID-19 patients were randomly assigned to placebo and Imfluna groups. Patients in each groups, in addition to receiving standard medications, took two 500 mg Imfluna capsules or placebo every 8 hours for 2 weeks. The patient's vital signs, pulmonary involvement, severity of shortness of breath, average blood CBC count, Percentage of blood oxygen saturation, liver and kidney function tests and study Na were evaluated. Results: The results showed that patients in the Imfluna-treated group had significantly greater improvement in pulmonary involvement, severity of shortness of breath, average blood CBC count, Percentage of blood oxygen saturation compared with the placebo group. Conclusion: Patients with COVID-19 who were treated with a Imfluna for 2 weeks had better comfort and fewer symptoms associated with the disease with no drug side effects.