The Role of the Microbiome in Pediatric Respiratory Diseases
Clinics in Chest Medicine(2024)
Abstract
Numerous studies have examined the role of the microbiome and microbiome-based therapeutics in many childhood airway and lung diseases. In this narrative review, the authors first give a brief overview of the current methods used in microbiome research. The authors then review the literature linking the microbiome with (1) early-life acute respiratory infections due to respiratory syncytial virus, (2) childhood asthma onset, (3) cystic fibrosis, and (4) bronchopulmonary dysplasia, focusing on recent studies that have used culture-independent methods to characterize the respiratory or gut microbiome in the pediatric population.
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Key words
Asthma,Bronchopulmonary dysplasia,Children,Chronic lung disease of prematurity,Cystic fibrosis,Microbiome,Pediatrics,Respiratory syncytial virus
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