Effect of Black Cumin (Nigella sativa) on Prostate Health: Narrative Review

Meshari A. Alzahrani, Ibrahim Abunohaiah, Yousuf Altuwaijry, Muath Alahmadi, Osama Qasim, Abdulaziz Alzahrani, Shamshad Begum Loni, Mohammed Shareef,Raed Almannie,Saleh Binsaleh

F1000Research(2024)

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摘要
A growing amount of research is shedding light on functional foods and nutritional supplements’ potential health and disease-preventative advantages. Black cumin (Nigella sativa L.), an esteemed nutraceutical herb, is well-known for its multiple health advantages among health-conscious individuals, researchers, and pharmaceutical businesses. Black cumin and its principal bioactive ingredient, thymoquinone (TQ), have been found to lower oxidative stress and inflammation, while also enhancing immunological function, cellular viability, and energy metabolism. They protect against metabolic, cardiovascular, digestive, hepatic, renal, pulmonary, reproductive, and neurological diseases, as well as cancer. Black cumin works as a countermeasure to minimize the toxicity and side effects of pharmaceuticals. Furthermore, the possible effects of black cumin on prostate health and disorders like benign prostatic hyperplasia and prostate cancer are not well understood. This narrative review seeks to reveal knowledge gaps. This study intends to guide future research into the possible uses of black cumin and TQ in prostate health and illness.
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