Overview of vasopressor and inotropic agents

Hypotension can often occur during and following anesthesia and surgery. Studies emphasize that end -organ ischemia during surgery is associated with morbidity, hypotension and mortality. Vasoactive agents and fluid volumes are often preferred to improve hypotension during surgery. Despite the widespread use of vasoactive agents, neither the substance nor the dose has been fully defined. Vasoactive agents are divided into two groups according to their functions: vasopressors and inotropes. These agents are believed to regulate end -organ perfusion. But, it also has side effects such as hyperlactataemia, tachycardia, tachyarrhythmias, ischemia and hyperglycemia. The likelihood and severity of these side effects depend on the agent used, its amount and duration. Our aim in this compilation is; To provide an overview of inotropic agents. To give information about ISO and dobutamine, which are inotropic agents, and to briefly touch upon their use in animal studies.