Identification of ADME Genes Polymorphic Variants Linked to Trastuzumab-Induced Cardiotoxicity in Breast Cancer Patients: Case Series of Mono-Institutional Experience

Nicoletta Staropoli,Francesca Scionti, Valentina Farenza, Federica Falcone,Francesco Luciano, Maria Renne,Maria Teresa Di Martino,Domenico Ciliberto, Ludovica Tedesco, Antonella Crispino,Caterina Labanca,Maria Cuce, Stefania Esposito,Giuseppe Agapito,Mario Cannataro,Pierfrancesco Tassone,Pierosandro Tagliaferri,Mariamena Arbitrio

BIOMEDICINE & PHARMACOTHERAPY（2024）

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Key words

ADME,absorption,distribution,metabolism and excretion genes,ADME genes polymorphic variants,trastuzumab,cardiotoxicity,anti-HER2,breast cancer,single nucleotide polymorphisms,SNPs

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