3D printed ventilation tubes and their effect on biological models

Luis Humberto Govea-Camacho, Irma Yolanda Castillo-López, Sergio Alejandro Carbajal-Castillo,Alejandro Gonzalez-Ojeda,Gabino Cervantes-Guevara, Enrique Cervantes-Pérez,Sol Ramírez-Ochoa, Sergio Jiram Vázquez-Sánchez, Gonzalo Delgado-Hernández, Jaime Alberto Tavares-Ortega, Samantha Emily González-Muñoz, Clotilde Fuentes-Orozco

3D Printing in Medicine(2024)

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摘要
Acute otitis media (AOM) causes inflammation and hearing loss. Ventilation tubes are key in treatment. 3D printing improves prostheses in otorhinolaryngology, offering precision and greater adaptability. An experimental study was conducted with Wistar rats from July to December 2020. 3D tympanostomy tube models were designed, with technical specifications and tests performed on inexpensive 3D printers. The tympanostomy tube was inserted endoscopically. Procedures were performed on five rats with implants in both ears. Pre-intervention pathologies, such as atical retraction and glue ear, were found. The PLA-printed tympanostomy tube showed improvement after adjustments. Histopathological results revealed significant middle and inner ear damage. In our study, the design and 3D printing of implants fulfilled the desired functions when modified, with a height of 5 mm. Complications included PLA degradation and ear damage. There were no adverse events during observation, highlighting the need for further research on 3D-printed implants.
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关键词
Implants,3D printing,Ventilation tubes,Acute otitis media
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