FIGURE 2 from Identification of Nonfunctional Alternatively Spliced Isoforms of STING in Human Acute Myeloid Leukemia
crossref(2024)
摘要
Evaluation of the STING pathway across common AML cell lines. A, Indicated AML cell lines plated 1 × 105 cells/well were stimulated 72 hours with CDNs at 10 µg/mL, and supernatants were harvested for ELISA (n = 5). An assay detection limit of 50 pg/mL is shown. qPCR analysis (B) and immunoblot (C) of STING pathway and resistance genes across AML lines (n = 1). For qPCR, data represent GAPDH-normalized fold expression relative to normal CD11b+ PBMC controls.
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