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Orthogonal IL-2/IL-2Rβ Signaling Selectively Enhances and Sustains a Synthetic Effector State Via a Novel Mechanism and Outperforms Constitutive Armoring Approaches

Ethan Jung, Helena Silva,Marie Semana, Ivan Cheng, Somya Singh,Michele Bauer,Mohammed Ali, Henry Rosas,Ryan Burgess, George Zeng, Woei Chang,Navneet Ratti,Deepti Rokkam,Patrick J. Lupardus,Martin Oft,Paul-Joseph Aspuria

Cancer Research（2024）

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