Drug-Resistant Tuberculosis, Georgia, Kazakhstan, Kyrgyzstan, Moldova, and Ukraine, 2017–2022

Victor Naestholt Dahl,Tetiana Butova,Alex Rosenthal, Alina Grinev,Andrei Gabrielian,Sergo Vashakidze,Natalia Shubladze, Bekzat Toxanbayeva, Lyailya Chingissova,Valeriu Crudu,Dumitru Chesov,Gulmira Kalmambetova, Gulbarchyn Saparova,Christian Morberg Wejse,Dmytro Butov

Emerging Infectious Diseases（2024）

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摘要

In 2021, the World Health Organization recommended new extensively drug-resistant (XDR) and pre-XDR tuberculosis (TB) definitions. In a recent cohort of TB patients in Eastern Europe, we show that XDR TB as currently defined is associated with exceptionally poor treatment outcomes, considerably worse than for the former definition (31% vs. 54% treatment success).

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关键词

tuberculosis and other mycobacteria,bacteria,multidrug-resistant tuberculosis,extensively drug-resistant tuberculosis,treatment outcome,disease management

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