Design of hybrid biomaterials using polymethacrylates grafted by ATRP-SI onto titanium for cranioplasty applications

Surface-initiated atom transfer radical polymerization created hybrid Ti sheet systems grafted with the poly(methyl methacrylate) (PMMA) family for biomedical application. This metal/polymer hybrid material exhibits strong bonding at the interface. While the first research concentrated on PMMA on millimeter-sized Ti samples, the technique was expanded to large-sized (100 × 200mm²) using methyl methacrylate (MMA) and also a blend of MMA and butyl methacrylate instead of the MMA during the polymerization step.