Recent advances in the development and applications of luminescent bacteria-based biosensors

Luminescent bacteria-based biosensors are widely used for fast and sensitive monitoring of food safety, water quality, and other environmental pollutions. Recent advancements in biomedical engineering technology have led to improved portability, integration, and intelligence of these biotoxicity assays. Moreover, genetic engineering has played a significant role in the development of recombinant luminescent bacterial biosensors, enhancing both detection accuracy and sensitivity. This review provides an overview of recent advances in the development and applications of novel luminescent bacteria-based biosensors, and future perspectives and challenges in the cutting-edge research, market translation, and practical applications of luminescent bacterial biosensing are discussed. Luminescent bacteria-based biosensors have proved to be a simple, rapid, sensitive, adaptable, and reproducible technology for toxicity assays, which have been widely utilized for the detection of various environmental pollutants in the past few decades. image