Correlation between triglyceride glucose-body mass index and hypertension in patients with acute coronary syndrome

Abstract The triglyceride glucose-body mass index (TyG-BMI index) is a simple, cost-effective, practical alternative marker for early detection of insulin resistance. However, studies on the relationship between TyG-BMI index and hypertension in patients with acute coronary syndrome (ACS) are limited. We investigated the relationship between TyG-BMI index and hypertension in patients with ACS. We included 2,635 patients with ACS. TyG-BMI index was grouped into tertiles. In the overall ACS population, after adjusting for covariates, multivariate logistic regression analyses showed that TyG-BMI index was an independent risk factor for hypertension in patients with ACS. In subgroup analyses, the TyG-BMI index was found to be an independent risk factor for hypertension in older, nondiabetic, and male ACS patients. Restricted cubic spline analysis revealed a nonlinear correlation between TyG-BMI index and hypertension in patients with ACS. The baseline risk model’s predictive power was not improved by the inclusion of TyG-BMI index in patients with ACS. TyG-BMI index was nonlinearly correlated with hypertension in patients with ACS, and the inclusion of TyG-BMI index did not enhance the predictive power of the baseline risk model in patients with ACS.