Draft genome of the Klebsiella pneumoniae 24Kpn33 and complete sequence of its pCOL-1, a plasmid related to the bla_KPC-2 acquisition in Pseudomonas aeruginosa

Deisy Abril, Duway Nicolas Lesmes-Leon,Ricaurte Alejandro Marquez-Ortiz,Aura Lucia Leal,Catalina Tovar-Acero,Zayda Lorena Corredor Rozo,Natasha Vanegas Gomez,Javier Escobar-Perez

MICROBIOLOGY RESOURCE ANNOUNCEMENTS（2024）

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摘要

We report the draft genome of a clinical multi-resistant Klebsiella pneumoniae (24Kpn33) isolate, whose genome (5.7 Mbp) harbored 17 antibiotic resistance genes, including blaKPC-2. Notably, this gene was mobilized within the IncP-6 pCOL-1 plasmid, the first genetic platform related to the acquisition and dissemination of the blaKPC-2 in Pseudomonas aeruginosa.

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关键词

bla(KPC-2),pCOL-1,Tn4401b,interspecies dissemination

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Draft genome of the Klebsiella pneumoniae 24Kpn33 and complete sequence of its pCOL-1, a plasmid related to the blaKPC-2 acquisition in Pseudomonas aeruginosa

Draft genome of the Klebsiella pneumoniae 24Kpn33 and complete sequence of its pCOL-1, a plasmid related to the bla_KPC-2 acquisition in Pseudomonas aeruginosa