Celldetective: an AI-enhanced image analysis tool for unraveling dynamic cell interactions

Rémy Torro, Beatriz Dìaz-Bello, Dalia El Arawi, Lorna Ammer,Patrick Chames,Kheya Sengupta,Laurent Limozin

biorxiv(2024)

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Abstract
A current key challenge in bioimaging is the analysis of multimodal and multidimensional data reporting dynamic interactions between diverse cell populations. We developed Celldetective, a software that integrates AI-based segmentation and tracking algorithms and automated signal analysis into a user-friendly graphical interface. It offers complete interactive visualization, annotation, and training capabilities. We demonstrate it by analyzing original experimental data of spreading immune effector cells as well as antibody-dependent cell cytotoxicity events using multimodal fluorescence microscopy. ### Competing Interest Statement The authors have declared no competing interest.
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