Significant thrombus in saccular aneurysm in a patient with polycythemia: a case report

Atsuyuki Mitsuishi, Hiromasa Nakamura,Yujiro Miura, Tsuyoshi Miyata,Kazumasa Orihashi,Keisuke Yoshida, Kouhei Araki

Journal of Cardiothoracic Surgery(2024)

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摘要
Morphologically, the risk of aortic aneurysm rupture is mainly evaluated based on its type (e.g., fusiform or saccular) and diameter. Based on the finite element analysis, peak wall stress has been identified as a more sensitive and specific predictor of rupture in recent years. Moreover, in finite analysis, the neck of aneurysm is the highest peak wall stress and is associated with the rupture point. A saccular aortic aneurysm (84 mm) was incidentally detected during preoperative examination for chronic empyema in a 74-year-old male patient with a history of polycythemia. Aortic arch graft replacement using an open stent was performed. Morphologically, this case was associated with a very high risk of rupture; nevertheless, it did not rupture. In this case, a mural thrombus (likely formed due to polycythemia) covered the neck of aneurysm that is experiencing the highest peak wall stress and is associated with the rupture point. The mural thrombus decreased peak wall stress and could reduce the risk of rupture even for huge saccular aneurysms. Furthermore, the mural thrombus was fully occupied in aneurysms, such as during coil embolization. Thus, polycythemia could decrease the risk of rupture of huge saccular aneurysms.
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关键词
Saccular aneurysm,Polycythemia,Mural thrombus,Peak wall stress,Endothelial cell,Rupture point,Vasa Vasorum,Case report
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