Photo- neuro- immuno- endocrinology: How the ultraviolet radiation regulates the body, brain, and immune system
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA(2024)
Abstract
we have gathered experimental and obser- vational evidence that UVR spectra of solar radiation have profound effects on systemic body homeostasis, which are defined by their wavelength and energy, nature of chromo- phores and of molecules produced in the barrier organ. Local physicochemical changes induced by solar radiation can lead to activation of local neuro- immuno- endocrine sensing and regulatory mechanisms with their projection to the central or systemic levels. While the precise mecha- nisms of these interactions remain to be explored, their health benefits and therapeutic implications can outweigh the negative effects if responsibly applied in an educated manner.
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Key words
ultraviolet radiation,skin,body homeostasis,neuroimmunoendocrinology,stress
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