SARS-CoV-2 seroprevalence among children in Greece during Omicron variant period

Dimitra Dimopoulou, Despoina Sotiri, Dimitra Kousi, Garyfallia Loulou, Kalliopi Raptaki, Ariadni Neofytou,Foteini Dasoula, Maria Tampouratzi, Athina Koloi, Eirini Eleftheriou,Eleni Vergadi, Eleni Papadimitriou, Irini Zorbadaki,Artemis Mavridi, Konstantinos Miliordos,Evangelia Steletou, Maria Strempela,Paraskevi C. Fragkou, Vassiliki Spoulou,Athanasios Michos,Despoina Gkentzi,Vassiliki Papaevangelou,Fani Ladomenou,Ioanna Grivea,George Syrogiannopoulos,Emmanouil Galanakis,Theoklis Zaoutis,Kyriaki Tryfinopoulou,Maria N. Tsolia

European Journal of Pediatrics（2024）

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摘要

The Omicron variant is associated with increased transmissibility, but evidence about the impact of Omicron in seropositivity of children is limited. This study aims to evaluate SARS-CoV-2 seroprevalence in children during the different variants’ subperiods. A prospective multicenter seroprevalence study was conducted in 7 University public hospitals in Greece from November 2021 to August 2022 (3 subperiods: November 2021-February 2022, March 2022-May 2022, June 2022-August 2022). Children from different age groups, admitted to the hospital or examined in outpatient clinics for reasons other than COVID-19 were enrolled. Neutralizing antibodies (Nabs), anti-Spike (anti-S) and anti-nucleocapsid (anti-N) SARS-CoV-2 IgG in serum were evaluated. A total of 2127 children (males:57,2

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关键词

COVID-19,SARS-CoV-2,Seroepidemiology,Seroprevalence,Variants,Omicron,Children

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