Evaluation of Vaccine Immunogenicity-Correlates to Real-World Protection: Influenza
VIRUSES-BASEL(2024)
摘要
Recent events highlighted that, despite decades of studying vaccine immunogenicity and efforts toward finding correlates of protection, evaluating real-world vaccine efficacy as well as establishing meaningful licensing criteria still represents a significant challenge. In this paper, we review all aspects of influenza vaccine immunogenicity, including animal and human challenge studies, humoral and cellular immunity parameters, and their potential correlation with real-life protection from disease.
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关键词
influenza,vaccine,immunity,antibody,lymphocyte
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