ncRS: A resource of non-coding RNAs in sepsis

Baocai Zhong, Yongfang Dai, Li Chen, Xinying Xu, Yuxi Lan, Leyao Deng,Liping Ren,Nanchao Luo,Lin Ning

Computers in Biology and Medicine(2024)

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摘要
Sepsis, a life-threatening condition triggered by the body's response to infection, presents a significant global healthcare challenge characterized by disarrayed host responses, widespread inflammation, organ impairment, and heightened mortality rates. This study introduces the ncRS database (http://www.ncrdb.cn), a meticulously curated repository housing 1144 experimentally validated non-coding RNAs (ncRNAs) intricately linked with sepsis. ncRS offers comprehensive RNA data, exhaustive experimental insights, and integrated annotations from diverse databases. This resource empowers researchers and clinicians to decipher ncRNAs' roles in sepsis pathogenesis, potentially identifying vital biomarkers for early diagnosis and prognosis, thus facilitating personalized treatments.
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关键词
Sepsis,Non-coding RNA,ncRS database,Pathogenesis,Biomarker
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