Multifunctional nanoparticles in stem cell therapy for cellular treating of kidney and liver diseases

Heba Mohamed Fahmy,Taiseer Mohamed Abd El-Daim, Heba Allah Abd El Nabi Eid Mohamed,Esraa Ahmed Abu El qassem Mahmoud, Eman Ahmed Sayed Abdallah, Fatma El-zahraa Mahmoud Hassan,Doaa Ibrahim Maihop, Aisha Edress Abd Elkhaleq Amin, Amira Bahaa ElDin Mustafa, Fatma Mohammed Ali Hassan, Dalia Mahmoud Ezzat Mohamed,Engy Maged Mohamed Shams-Eldin

Tissue and Cell（2020）

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摘要

•Trails about using nanoparticles in stem cell therapy in kidney and liver diseases were indicated.•An overview of the mechanisms of distribution of nanoparticles in stem cells was achieved.•Tracking the fate of transplanted stem cells by using various techniques also was discussed.•The distinctive strategies to enhance homing of labeled stem cells with nanoparticles were explained.•How to improve nanoparticles uptake by making modifications to iron coat was illustrated.

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关键词

Stem cells,Mesenchymal stem cells,Nanoparticles,Tracking,Homing

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