Clinical Evaluation of a New Spectral-Domain Optical Coherence Tomography-Based Biometer

Jorge L. Alió, Marina José-Martínez, Antonio Martínez-Abad, Alejandra E. Rodríguez, Francesco Versaci, Jesper Hjortdal, Joaquim Neto Murta, Ana B. Plaza-Puche, Mario Cantó-Cerdán, David P. Piñero

Diagnostics(2024)

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摘要
The VEMoS-AXL system is a new optical biometer based on spectral domain optical coherence tomography (SD-OCT) that has been tested in terms of intrasession repeatability and compared with a swept-source optical coherence tomography biometer (SS-OCT), which is recognized as the gold standard for the performance of an agreement analysis. A biometric analysis was performed three consecutive times in 120 healthy eyes of 120 patients aged between 18 and 40 years with the SD-OCT system, and afterwards, a single measurement was obtained with the SS-OCT system. Within-subject standard deviations were 0.004 mm, 4.394 µm, and 0.017 mm for axial length (AL), central corneal thickness (CCT), and anterior chamber depth (ACD) measures obtained with the SD-OCT biometer, respectively. The agreement between devices was good for AL (limits of agreement, LoA: −0.04 to 0.03 mm) and CCT (LoA: −4.36 to 14.38 µm), whereas differences between devices were clinically relevant for ACD (LoA: 0.03 to 0.21 mm). In conclusion, the VEMoS-AXL system provides consistent measures of anatomical parameters, being most of them interchangeable with those provided by the SS-OCT-based gold standard.
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关键词
optical biometry,axial length,anterior chamber depth,central corneal thickness,swept-source optical coherence tomography,spectral-domain optical coherence tomography
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