Direct induction onto high-dose long-acting injectable buprenorphine: A case series
Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists(2024)
摘要
Introduction This case series reports on five patients with opioid use disorder (OUD) who were commenced directly onto high-dose long-acting injectable buprenorphine (LAIB).Method A retrospective audit and manual review of the electronic medical record at cohealth Innerspace was conducted for patients who had been directly inducted onto high-dose LAIB.Results Five cases were identified on retrospective manual file review. All patients identified were males aged between 33 and 60 years old and were treated with either high-dose Buvidal Weekly and Monthly preparations. No immediate significant adverse effects were noticed and 4 out of 5 remain engaged with treatment.Conclusion This case series shows it is possible to directly induct patients with OUD onto high-dose LAIB preparations without significant side effects or harm to the patient and could be considered a viable option in the treatment of patients with OUD.
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关键词
buprenorphine,long-acting injectable buprenorphine,opioid use disorder,opioid substitution therapy,opioid agonist therapy,high-dose induction,medication assisted treatment for opioid dependence
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