Enhancing Systemic Translocation of Insecticides via Nanoformulations Incorporating -Cyclodextrin Octadecarboxylate as a Carrier

The conversion of contact-killing pesticides into systemic pesticides can significantly enhance the bioavailability of pesticides, thereby reducing pesticide usage and environmental harm. A series of beta-cyclodextrin fatty acid esters with varying branch chains were synthesized and employed as carriers in nanoformulation of insecticide. The investigation revealed that nanoformulations prepared using beta-cyclodextrin octadecarboxylate (beta-CDs) exhibited superior stability and remarkable systemic translocation within plants. Six contact-killing insecticide nanoformulations were developed utilizing beta-CDs as carriers, and tests indicated that beta-CDs significantly enhanced the systemic translocation of insecticides in plants compared to carrier-free nanoformulations. It was found that beta-CDs increased the level of systemic translocation of insecticides by 5-12 times. Additionally, characterization results from lambda-cyhalothrin-beta-CDs nanoformulation demonstrated their superior ability to improve photolysis resistance, prolong release time, and extend insecticidal duration. Consequently, beta-CDs can be utilized as a green additive in pesticide production to enhance the systemic translocation of pesticides in plants and increase their bioavailability.