Evaluation of Completeness of Information in Patient Information Leaflets of Registered Medications: A Comprehensive Review

Patient information leaflets includes information about the appropriate usage of medication. The information provided in the leaflet should be easy to understand. Moreover, the information needs to be comprehensive to guide the healthcare professionals to ensure the optimal use of medication. The current study aimed to assess the completeness of information mentioned in the medication leaflets. The medication leaflets of tablet dosage forms of local pharmaceutical companies were collected and assessed for various parameters such dosing of medication, drug interaction, medication safety, storage instructions, adverse effects etc. a total of 187 leaflets were assessed for completeness of information. Information about renal and hepatic dose adjustment was present in only 32% leaflets. The maximum dose per day was missing in about half of the studied leaflets. The instructions about use in lactation period was mentioned in around 71% leaflets. Drug food interactions were mentioned in only 3.2% leaflets. Drug-drug interactions were missing in around onethird leaflets. The instructions about food needs to be avoided with medication administration was stated in only 6.5% leaflets. Pharmacokinetics parameter was observed in around 56.6% leaflets. The study concludes that most of the leaflets lack some of the important medication information.