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Early Process Development of PF-07054894, a Squaramide-Based Antagonist of C–C Chemokine Receptor Type 6 (CCR6)

Gary M. Chinigo,Emma L. Mcinturff,Scott W. Bagley,Richard W. Barnhart,David C. Blakemore, Lu Han,Taegyo Lee,Javier Magano,J. Christopher McWilliams,Sebastien Monfette,James J. Mousseau, Senliang Pan,Dylan Pedro,Hahdi H. Perfect,Jeffrey W. Raggon, Peter R. Rose,John Sagal,John I. Trujillo, Jared Van Haitsma,Michael G. Vetelino, Xiaojing Helen Yang

ORGANIC PROCESS RESEARCH & DEVELOPMENT（2024）

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Key words
CCR6,CCR6antagonist,squaramide,sulfinimine addition,hydroxy aminopyridine,squaramidebisaddition
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