Clinical characteristics and predictive factors of delayed diagnosis in patients with sellar germ cell tumors

Journal of Neuro-Oncology(2024)

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Abstract
To investigate the clinical characteristics and predictive factors associated with delayed diagnosis in patients with sellar germ cell tumors (GCTs), aiming for early diagnosis. A total of 345 patients with sellar GCTs were retrospectively collected. Patients were classified into a delayed diagnosis group (> 6 months from onset to diagnosis) and a non-delayed diagnosis group (≤ 6 months). We compared general characteristics, clinical symptoms, diagnostic methods, treatment strategies, tumor prognosis, and pituitary function between the two groups. Predictive factors for delayed diagnosis were explored using multivariate logistic regression analysis. 225 patients (65.2
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Key words
Intracranial germ cell tumors,Children and adolescents,Delayed diagnosis,Pituitary function,Predictive factors
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