Flexible ureteroscopic treatment of kidney stones: How do the new laser systems change our concepts?

Asian Journal of Urology(2024)

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Abstract
Objective Flexible ureteroscopy (fURS) has become a widely accepted and effective technique for treating kidney stones. With the development of new laser systems, the fURS approach has evolved significantly. This literature review examines the current state of knowledge on fURS treatment of kidney stones, with a particular focus on the impact of the latest laser technologies on clinical outcomes and patient safety. Methods We conducted a search of the PubMed, Medline, Web of Science Core Collection, SCOPUS, Embase (OVID), and Cochrane Databases for all randomized controlled trial articles on laser lithotripsy. Results We found a total of 22 relevant pieces of literature. Holmium laser has been used for intracavitary laser lithotripsy for nearly 30 years and has become the golden standard for the treatment of urinary stones. However, the existing holmium laser cannot completely powder the stone, and the retropulsion of the stone after the laser emission and the thermal damage to the tissue has caused many problems for clinicians. The introduction of thulium fiber laser and Moses technology brings highly efficient dusting lithotripsy effect through laser innovation, limiting pulse energy and broadening pulse frequency. Conclusion In this study, we summarize the current research status and new progress of laser lithotripsy and consider the selection of physical parameters from the development of existing lasers to explore the broader prospect of laser lithotripsy of urinary stones.
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Key words
Laser lithotripsy,Urolithiasis,Thulium lasers,Holmium: yttrium--aluminum—garnet,Moses effect
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