[Recent research on the role of oxidative stress in the pathogenesis of attention deficit hyperactivity disorder].

Chen-Lei Wu, Meng-Fei Wang,Rong-Yi Zhou

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics(2024)

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Abstract
Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in children and adolescents, and its etiology and pathogenesis are still unclear. Brain is the organ with the largest oxygen consumption in human body and is easily affected by oxidative imbalance. Oxidative stress has become the key research direction for the pathogenesis of ADHD, but there is still a lack of relevant studies in China. Based on the latest research findings in China and overseas, this article reviews the clinical and experimental studies on oxidative stress in ADHD and explores the association of oxidative stress with neurotransmitter imbalance, neuroinflammation, and cell apoptosis in the pathogenesis of ADHD, so as to provide new research ideas for exploring the pathogenesis of ADHD.
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Key words
Attention deficit hyperactivity disorder,Oxidative stress,Neurotransmitter,Neuroinflammation,Cell apoptosis
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