Treatment-free remission in CML patients with additional chromosome abnormalities in the Philadelphia-positive clone or variant Philadelphia translocations

Simone Claudiani,Lynette Chee,Fiona Fernando, Loretta Brown, Udayakumar M. Achandira,Afzal Khan, Kate Rothwell,Chloe Hayden, Ioannis Koutsavlis, Guy Hannah,Andrew Innes,Jane F. Apperley,Dragana Milojkovic

AMERICAN JOURNAL OF HEMATOLOGY(2024)

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摘要
Probability of treatment-free remission (TFR) in CML patients with additional chromosomal abnormalities (ACA) in the Philadelphia-positive clone or variant Philadelphia translocations (ACA/Var-Ph group, blue panel), in those with no cytogenetic abnormality other than the classical Philadelphia translocation (c-Ph group, green panel) and in the subgroups of CML patients with high-risk ACA (HR-ACA, yellow panel) and Var-Ph (red panel).
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