Biomimetic ECM-Based Hybrid Scaffold for Cartilage Tissue Engineering Applications
Journal of Polymers and the Environment(2024)
摘要
Conventional methods have failed to show the ability of articular cartilage to completely restore. Decellularized extracellular matrix has achieved interest as a potential biomaterial for cartilage tissue engineering approaches. The decellularized cartilage-derived matrix (CDM) scaffolds retain the native composition of cartilage tissue, providing a conducive microenvironment for cellular growth and differentiation, while exhibit limited mechanical support. Our investigation involved the fabrication of a new hybrid CDM- polyvinyl alcohol (PVA) hydrogel scaffold with four different concentrations (5
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关键词
Osteoarthritis,Cartilage,Tissue engineering,Decellularized,CDM
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