SBRT-SG-01: final results of a prospective multicenter study on stereotactic body radiotherapy for liver metastases

María-Carmen Rubio Rodríguez,Xin Chen-Zhao,Ovidio Hernando, Sonia Flamarique,Pedro Fernández-Letón,Maider Campo,Mercedes López,Maitane Rodríguez,Daniel Zucca, Daniel Martínez, Emilio Sánchez-Saugar, Fernando Mañeru, Juan García Ruiz-Zorrilla,Paz García de Acilu,Jeannette Valero,Angel Montero,Raquel Ciérvide,Beatriz Alvarez,Mariola García-Aranda,Rosa Alonso,Miguel Angel de la Casa,Leyre Alonso, Mónica Nuñez,Jaime Martí,Fernando Arias

Clinical and Translational Oncology（2024）

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Abstract

This study aimed to assess the efficacy and tolerability of stereotactic body radiation therapy (SBRT) for the treatment of liver metastases. Patients with up to 5 liver metastases were enrolled in this prospective multicenter study and underwent SBRT. Efficacy outcomes included in-field local control (LC), progression-free survival (PFS), and overall survival (OS). Acute and late toxicities were evaluated using CTCAE v.4.0. A total of 52 patients with 105 liver metastases were treated between 2015 and 2018. The most common primary tumor was colorectal cancer (72

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Key words

SBRT,Liver metastases,Oligometastases

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