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Oral manifestations in women using hormonal contraceptive methods: a systematic review

CLINICAL ORAL INVESTIGATIONS(2024)

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Abstract
ObjectivesTo investigate the oral manifestations in women of reproductive age using hormonal contraceptive methods.Materials and methodsThis review is based on the PRISMA statement. A literature search incorporated observational studies from the last 21 years. An investigative question was formulated using the PICO model, studies were selected, and a quality analysis was performed using the modified STROBE guidelines. A bibliometric analysis was performed, and the data were examined.ResultsThirteen articles were included, with the majority evaluating periodontal status. Others analyzed factors such as the presence of alveolar osteitis, oral candidiasis, and salivary microbiome dysbiosis. Ten articles were deemed to have a low risk of bias.ConclusionsHormonal contraceptives may increase the risk of alveolar osteitis following tooth extraction and increase the presence of the Candida species in the oral cavity. They also affect the periodontium, such as the frequent development of gingivitis, but do not lead to changes in the salivary microbiome.Clinical relevanceThe increasing number of women using hormonal contraceptives and the knowledge that these contraceptives can produce oral cavity alterations underscore the need to evaluate the oral manifestations found in these women.
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Key words
Hormonal contraceptives,Oral manifestations,Periodontal disease,Alveolar osteitis,Oral candidiasis,Salivary microbiome
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