Two new cassane diterpenoids from the seed kernels of Caesalpinia sinensis
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH(2024)
摘要
Two new cassane diterpenoids, sucupiranin MN (1) and sucupiranin ML (2), together with two known compounds sucutinirane C (3) and deacetylsucutinirane C (4) were isolated from the seed kernels of Caesalpinia sinensis. Their structures were elucidated by means of analysis of comprehensive spectroscopic data, especially HRESIMS and 1D/2D NMR spectroscopy. Compounds 1-4 are typical furan-type cassane derivatives with an aromatized C ring. Biological evaluation revealed that compounds 1-4 at the concentration of 10 mu M could inhibit the overproduction of NO in LPS-stimulated RAW 264.7 macrophages. [Graphical abstract]
更多查看译文
关键词
Leguminosae,Caesalpinia sinensis,cassane diterpenoids,C ring aromatized,anti-inflammatory activity
AI 理解论文
溯源树
样例
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要