Aniline derivatives containing a cage monoterpenoid fragment at the nitrogen atom: synthesis and study of antibacterial properties

New camphor and fenchon anils, promising materials for the needs of medicine and industry, as well as some of their reduced forms, were synthesized and characterized. In a number of cases, the reduction by the NaBH 4 —NiCl 2 • 6H 2 O reagent system in EtOH containing water was accompanied by the formation of side products of the aromatic ring hydrogenation in up to 10–18% yields. Aniline derivatives containing a cage monoterpenoid fragment at the nitrogen atom were studied for antibiotic activity in vitro against gram-positive and gram-negative bacteria, yeasts, and imperfect fungi. The results obtained in the Halobacterium salinarum test system allowed us to identify the most active compounds and draw a conclusion about good prospects for the further structural modification in this chemotype series of compounds.