Overview of canine eosinophilic lung and bronchial diseases
TIERAERZTLICHE PRAXIS AUSGABE KLEINTIERE HEIMTIERE(2024)
摘要
In dogs with chronic cough eosinophilic lung disease (ELD) may be present, especially in young dogs. A breed predisposition has been described in Alaskan Malamutes and Siberian Huskies. Chronic cough is the most common clinical sign. Other symptoms include nasal discharge, sneezing, poly- or dyspnea and exercise intolerance. The exact pathogenesis is unknown. Type 1 hypersensitivity reaction is suspected. Eosinophilic lung diseases may be classified into different groups (eosinophilic bronchitis, eosinophilic bronchopneumopathy and eosinophilic granuloma). Diagnostic work-up includes hematology, imaging, bronchoscopy and cytologic examination of bronchoalveolar lavage fluid. A wide spectrum is present in terms of the expression and severity of the changes. The current reported treatment is systemic or inhaled glucocorticoids, or a combination of both. Most patients respond well to therapy. Relapses after treatment discontinuation are common.
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关键词
Respiratory disease,glucocorticoids,chronic cough,hypersensitivity reaction,inhaled therapy
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