In situ single-cell profiling sheds light on IFI27 localisation during SARS-CoV-2 infection

Chin Wee Tan, Jinjin Chen,Ning Liu,Dharmesh D. Bhuva,Tony Blick,James Monkman,Caroline Cooper,Malvika Kharbanda,Kristen Feher,Belinda Phipson,Emily E. Killingbeck,Liuliu Pan,Youngmi Kim,Yan Liang,Andy Nam, Michael Leon,Paulo Souza-Fonseca-Guimaraes,Seigo Nagashima,Ana Paula Camargo Martins,Cleber Machado-Souza

eBioMedicine（2024）

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摘要

The utilization of single-cell resolved spatial transcriptomics to delineate immune responses during SARS-CoV-2 infection was able to identify M1 macrophages to have elevated expression of IFI27 in areas of infection.

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