Peptidyl-tRNA hydrolase as a key player in the liberation of truncated nascent chains from the ribosomal subunit

Svetlov et al. identify the enzyme peptidyl-tRNA hydrolase as a ribosome -associated quality -control factor that promotes hydrolysis of the dislodged peptidyl-tRNA, which helps to recycle ribosomal subunits blocked by truncated nascent chains in bacteria.