Evaluation of interleukins (IL-1α, IL-1Ra, IL-12, IL-17A, IL-31, and IL-33) and chemokines (CXCL10 and CXCL16) in the serum of male patients with ankylosing spondylitis
International immunopharmacology(2024)
Abstract
•Serum levels of IL-17A, CXCL10, and CXCL16 were up-regulated in male patients with ankylosing spondylitis.•Serum IL-31 levels were down-regulated in in male patients with ankylosing spondylitis.•IL-17A, IL-31, CXCL10, and CXCL16 were potential markers to differentiate between ankylosing spondylitis patients and controls.•IL-1α, IL-1Ra, IL-12, and IL-33 levels showed no significant variations between ankylosing spondylitis patients and controls.
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Key words
Ankylosing spondylitis,Interleukin,Chemokine,Odds ratio,Area under the curve
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