Additive-free aerobic oxidative difunctionalization of alkenes with P₄S₁₀ and alcohols to access -hydroxy phosphorodithioates

An efficient strategy has been exploited for the synthesis of beta-hydroxy phosphorodithioates via additive-free aerobic oxidative difunctionalization of alkenes with P4S10 and alcohols at room temperature. This transformation provides a facile approach to access a series of beta-hydroxy phosphorodithioates in moderate to good yields by using eco-friendly air (O-2) as the sole oxidant and oxygen source. Notably, the hydrophosphorodithiolation products could be efficiently and selectively obtained when 2-vinylpyridine and alpha,beta-unsaturated carbonyl compounds were utilized in this reaction system.