Synthesis of Selenocyanated Indoles via PhICl2-Induced Electrophilic Intramolecular Cyclization of 2-Alkynylanilines or 2-Alkenylanilines
ASIAN JOURNAL OF ORGANIC CHEMISTRY(2024)
Abstract
The 3-selenocyanato-substituted indoles were readily synthesized via (dichloroiodo)benzene (PhICl2)-induced reaction of 2-alkynylanilines or 2-alkenylanilines with KSeCN in MeCN under metal-free conditions. The reaction sequence was postulated to encompass the formation of a reactive selenocyanogen chloride species, generated in situ from the reaction of PhICl2 and KseCN, followed by electrophilic addition and intramolecular cyclization steps.
MoreTranslated text
Key words
PhICl2,KSeCN,Indole,Intramolecular cyclization,Selenocynation Cyclization
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined