Exploring the potential benefits of shaoyao gancao decoction in athletes with gastric ulcer: a network pharmacology study

Jie Wang,Yu Li, Yuanmin Li, Wenli Zheng

REVISTA INTERNACIONAL DE MEDICINA Y CIENCIAS DE LA ACTIVIDAD FISICA Y DEL DEPORTE(2023)

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摘要
This study delves into the mechanism of action of Shaoyao Gancao Decoction, a traditional Chinese herbal remedy, in addressing gastric ulcers. Utilizing a network pharmacology approach, we investigate the potential benefits of this decoction, particularly in the context of athletes and their unique psychological and physiological demands. Gastric ulcers can significantly impact an athlete's performance and overall well-being due to the physical and psychological stressors associated with sports activities. Understanding the mechanism by which Shaoyao Gancao Decoction may mitigate gastric ulcers in this specific population is essential for enhancing their healthcare and performance outcomes. Through a comprehensive analysis of the herbal components of Shaoyao Gancao Decoction and their potential targets, we aim to uncover the intricate network of interactions that underlie its therapeutic effects. This research not only sheds light on the potential benefits of traditional herbal remedies in sports medicine but also offers valuable insights into the psychological aspects of athletes' well-being, as psychological stress is known to influence gastric health. By bridging the gap between traditional herbal medicine, sports, and psychology, this study contributes to a more holistic understanding of how Shaoyao Gancao Decoction may play a role in supporting athletes' gastrointestinal health and psychological resilience in the face of sporting challenges.
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关键词
Shaoyao Gancao Decoction,gastric ulcer,network pharmacology,signaling pathway,mechanism of action,Athlete healthcare,Sports medicine
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