Autism spectrum disorder - the possible trigger of pharmacological interventions used in infertility treatments or during pregnancy

Valentin Nicolae Varlas,Ovidiu Penes, Roxana Georgiana Varlas,Dragos Cretoiu,Anne-Marie Ciobanu,Nicolae Suciu, Anca Pop, Bruno Stefan Velescu, Cora Zetu

FARMACIA(2023)

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Abstract
The prescription of drugs for the treatment of infertility or during pregnancy has seen a sharp increase in recent years. The study aimed to review the main drugs used to evaluate the balance of benefits/risks of preconception during infertility treatment or during pregnancy. A 10-year PubMed database was searched to assess the association between medication use and offspring health outcomes. Careful analysis of pharmacovigilance reports regarding the potential risk of certain classes of drugs administered during infertility treatments or during pregnancy and ASD is the main strategy regarding the appropriate neurodevelopment of the offspring.
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Key words
autism spectrum disorder,infertility drugs,ART,pregnancy,perinatal pharmacological exposure,foetal brain development,maternal medication,child neurodevelopment
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